HPVomics

Efficient putative LR-HPVs E8^E2 protein epitopes (MHC-I Binders)

S.No.	HPV type	Target region	Peptide seuences	Start	End	Length	Allele	Percentile rank	ann_ic50	smm_ic50
1	HPV6	E8^E2	ALCVAHIGPV	62	71	10	HLA-A*02:03	0.2	6.24	12.48
2	HPV6	E8^E2	ESNCLKCFR	105	113	9	HLA-A*68:01	0.2	8.12	12.46
3	HPV6	E8^E2	ESNCLKCFR	105	113	9	HLA-A*33:01	0.25	14.15	38.38
4	HPV6	E8^E2	STLVSSSTK	32	40	9	HLA-A*11:01	0.3	10.22	34.14
5	HPV6	E8^E2	STWHWASSK	129	137	9	HLA-A*11:01	0.3	9.28	27.82
6	HPV6	E8^E2	VTYDSEEQR	147	155	9	HLA-A*68:01	0.35	15.58	26.33
7	HPV6	E8^E2	YTPAQTSTLV	26	35	10	HLA-A*68:02	0.55	25.36	33.14
8	HPV11	E8^E2	LTYSSEEQR	144	152	9	HLA-A*68:01	0.2	11.27	15.29
9	HPV11	E8^E2	RYRLNDKYK	110	118	9	HLA-A*30:01	0.2	4.65	9.16
10	HPV11	E8^E2	DSNCLKCFR	102	110	9	HLA-A*33:01	0.25	14.66	31.85
11	HPV11	E8^E2	DSNCLKCFR	102	110	9	HLA-A*68:01	0.4	16.01	27.13
12	HPV40	E8^E2	EANCLKCFR	113	121	9	HLA-A*68:01	0.15	6.53	8.18
13	HPV40	E8^E2	EANCLKCFR	113	121	9	HLA-A*33:01	0.2	11.5	23.02
14	HPV40	E8^E2	LTYSSVQQR	154	162	9	HLA-A*68:01	0.45	18.96	27.76
15	HPV40	E8^E2	AIITLTYSSV	150	159	10	HLA-A*02:03	0.55	24.55	19.02
16	HPV40	E8^E2	LTYSSVQQR	154	162	9	HLA-A*31:01	0.55	26.27	33.53
17	HPV42	E8^E2	AILKWKYSR	2	10	9	HLA-A*31:01	0.25	7.53	19.47
18	HPV42	E8^E2	SVDPGLCGV	95	103	9	HLA-A*02:06	0.3	5.72	12.84
19	HPV42	E8^E2	MAILKWKYSR	1	10	10	HLA-A*31:01	0.3	14.94	25.55
20	HPV42	E8^E2	ASVDPGLCGV	94	103	10	HLA-A*02:06	0.35	28.8	34.91
21	HPV42	E8^E2	TQVSSTWHL	150	158	9	HLA-A*02:06	0.4	8.21	19.52
22	HPV42	E8^E2	RTNSENCNK	104	112	9	HLA-A*30:01	0.4	6.67	20.37
23	HPV42	E8^E2	MAILKWKYSR	1	10	10	HLA-A*68:01	0.5	23.59	21.73
24	HPV42	E8^E2	TSPPRKRYR	63	71	9	HLA-A*31:01	0.6	29.79	38.32
25	HPV43	E8^E2	EANALKCFR	109	117	9	HLA-A*68:01	0.15	6.87	7.51
26	HPV43	E8^E2	EANALKCFR	109	117	9	HLA-A*33:01	0.2	14.15	24.05
27	HPV43	E8^E2	RVKIPITIK	165	173	9	HLA-A*30:01	0.2	7.76	10.71
28	HPV43	E8^E2	NTALITLTYI	145	154	10	HLA-A*68:02	0.25	5.54	21.25
29	HPV43	E8^E2	HTTPIADLAR	59	68	10	HLA-A*68:01	0.25	8.05	22.39
30	HPV43	E8^E2	NALKCFRYR	111	119	9	HLA-A*33:01	0.25	19.45	23.77
31	HPV43	E8^E2	SSDSRLVPK	77	85	9	HLA-A*11:01	0.35	14.16	37.52
32	HPV43	E8^E2	NALKCFRYR	111	119	9	HLA-A*31:01	0.55	26.78	31.22
33	HPV43	E8^E2	KCFRYRLNK	114	122	9	HLA-A*30:01	0.7	20.99	38.81
34	HPV44	E8^E2	VAASSTWRW	133	141	9	HLA-B*53:01	0.2	31.81	36.13
35	HPV44	E8^E2	FVAASSTWR	132	140	9	HLA-A*68:01	0.2	5.78	12.32
36	HPV44	E8^E2	VAASSTWRW	133	141	9	HLA-B*57:01	0.2	11.11	26.35
37	HPV44	E8^E2	VAASSTWRW	133	141	9	HLA-B*58:01	0.2	2.18	2.13
38	HPV44	E8^E2	RYRLHAKYK	121	129	9	HLA-A*30:01	0.2	2.5	4.42
39	HPV44	E8^E2	DANCLKCLR	113	121	9	HLA-A*33:01	0.25	23.36	24.1
40	HPV44	E8^E2	DANCLKCLR	113	121	9	HLA-A*68:01	0.45	21.09	25.85
41	HPV44	E8^E2	KYKTLFVAA	127	135	9	HLA-A*30:01	0.5	13.04	30.69
42	HPV44	E8^E2	HAKYKTLFV	125	133	9	HLA-A*30:01	0.7	5.34	38.28
43	HPV44	E8^E2	SSNALVTLTY	147	156	10	HLA-B*15:01	1.2	28.69	28.07
44	HPV54	E8^E2	DTTPIVHFK	93	101	9	HLA-A*68:01	0.15	4.63	4.6
45	HPV54	E8^E2	LTYSSVEQR	145	153	9	HLA-A*68:01	0.2	9.14	12.75
46	HPV54	E8^E2	RQQFLVTVR	153	161	9	HLA-A*31:01	0.2	10.54	9.52
47	HPV54	E8^E2	MAILTWKLR	1	9	9	HLA-A*68:01	0.4	22.77	15.29
48	HPV54	E8^E2	KCFRQRIQK	108	116	9	HLA-A*30:01	0.6	20.66	35.97
49	HPV54	E8^E2	LTYSSVEQR	145	153	9	HLA-A*31:01	0.6	26.13	37.45
50	HPV54	E8^E2	SMSLGVMSL	167	175	9	HLA-A*02:03	0.7	13.86	24.54
51	HPV61	E8^E2	IQATAGYMSM	179	188	10	HLA-B*15:01	0.1	8.86	0.53
52	HPV61	E8^E2	KQFLNRVTI	167	175	9	HLA-A*32:01	0.1	8.98	2.67
53	HPV61	E8^E2	RAAFVTLWY	152	160	9	HLA-B*58:01	0.2	9.95	36.75
54	HPV61	E8^E2	RAAFVTLWYV	152	161	10	HLA-A*02:06	0.25	18.73	21.62
55	HPV61	E8^E2	STSVQTPPHK	51	60	10	HLA-A*11:01	0.25	21.91	8.43
56	HPV61	E8^E2	YSSPVIHLK	106	114	9	HLA-A*68:01	0.35	6.89	28.41
57	HPV61	E8^E2	YSSPVIHLK	106	114	9	HLA-A*11:01	0.35	11.81	28.99
58	HPV61	E8^E2	STAETAGHLR	23	32	10	HLA-A*68:01	0.35	15.33	10.33
59	HPV61	E8^E2	AAFVTLWYV	153	161	9	HLA-A*02:06	0.45	5.17	23.91
60	HPV61	E8^E2	RAAFVTLWYV	152	161	10	HLA-A*68:02	0.55	35	35.02
61	HPV61	E8^E2	TAETAGHLR	24	32	9	HLA-A*68:01	0.6	35.34	34.87
62	HPV61	E8^E2	FVTLWYVNV	155	163	9	HLA-A*68:02	0.6	23.23	33.93
63	HPV70	E8^E2	DTTPIVHLK	84	92	9	HLA-A*68:01	0.15	6.03	6.68
64	HPV70	E8^E2	YENISCTWHW	112	121	10	HLA-B*44:02	0.15	5.85	31.11
65	HPV70	E8^E2	ETVRIPPSV	148	156	9	HLA-A*68:02	0.2	5.39	12.75
66	HPV70	E8^E2	KTKSAPSCK	44	52	9	HLA-A*30:01	0.2	2.43	3.18
67	HPV70	E8^E2	YRLRKFNSL	103	111	9	HLA-B*08:01	0.2	4.63	20.63
68	HPV70	E8^E2	RPSETDGVF	57	65	9	HLA-B*07:02	0.3	35.04	39.16
69	HPV70	E8^E2	RQKFLETVR	143	151	9	HLA-A*31:01	0.35	12.64	13.82
70	HPV70	E8^E2	HTAATTPCTK	34	43	10	HLA-A*68:01	0.35	18.95	14
71	HPV70	E8^E2	TVTYTTEAQR	134	143	10	HLA-A*68:01	0.4	10.78	36.39
72	HPV70	E8^E2	ETDGVFVDLV	60	69	10	HLA-A*68:02	0.5	16.64	29.47
73	HPV70	E8^E2	VTYTTEAQR	135	143	9	HLA-A*68:01	0.5	14.55	31.73
74	HPV70	E8^E2	TAATTPCTK	35	43	9	HLA-A*68:01	0.6	21.61	38.33
75	HPV70	E8^E2	VTYTTEAQR	135	143	9	HLA-A*31:01	0.6	38.43	35.03
76	HPV72	E8^E2	IQATAGYMSM	181	190	10	HLA-B*15:01	0.1	8.86	0.53
77	HPV72	E8^E2	SSSVQTPPCK	50	59	10	HLA-A*11:01	0.3	32.03	24.15
78	HPV72	E8^E2	EVPTVETVGR	21	30	10	HLA-A*68:01	0.4	24.59	12.82
79	HPV72	E8^E2	LKASSTWHW	138	146	9	HLA-B*58:01	0.4	16.98	38.31
80	HPV81	E8^E2	IQAMQGFMSM	177	186	10	HLA-B*15:01	0.1	4.31	0.4
81	HPV81	E8^E2	YPHSTETRNF	91	100	10	HLA-B*53:01	0.1	25.18	20.55
82	HPV81	E8^E2	GPAKTTKAPV	45	54	10	HLA-B*07:02	0.15	36.62	33.95
83	HPV81	E8^E2	DTAPVIHLR	104	112	9	HLA-A*68:01	0.15	3.7	2.28
84	HPV81	E8^E2	KLKCLRYRLR	117	126	10	HLA-A*31:01	0.15	6.23	10.82
85	HPV81	E8^E2	DTAPPNIWV	73	81	9	HLA-A*68:02	0.2	5.04	11.74
86	HPV81	E8^E2	DTAPVIHLR	104	112	9	HLA-A*33:01	0.25	21.86	8.85
87	HPV81	E8^E2	VNASSTWHW	134	142	9	HLA-B*58:01	0.3	9.04	21.79
88	HPV81	E8^E2	STQHVGPAK	40	48	9	HLA-A*11:01	0.35	16.32	35.1
89	HPV81	E8^E2	FSDGDTAPV	100	108	9	HLA-A*02:06	0.4	9.79	18.47
90	HPV81	E8^E2	EVSPAEAADR	21	30	10	HLA-A*68:01	0.5	29.63	24.32
91	HPV81	E8^E2	DANKLKCLR	114	122	9	HLA-A*68:01	0.55	32.62	29.68
92	HPV81	E8^E2	RLRSSVPHLF	124	133	10	HLA-B*15:01	0.95	11.54	23.29